β-Actin specifically controls cell growth, migration, and the G-actin pool
Targeted deletion of Actb demonstrates that the β-actin gene, in contrast to the γ-actin gene, is an essential gene uniquely required for cell growth and migration. Cell motility and growth defects in β-actin–knockout primary cells are due to a specific role for β-actin in regulating gene expression...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204067/ |