The utrophin actin-binding domain binds F-actin in two different modes: implications for the spectrin superfamily of proteins
Utrophin, like its homologue dystrophin, forms a link between the actin cytoskeleton and the extracellular matrix. We have used a new method of image analysis to reconstruct actin filaments decorated with the actin-binding domain of utrophin, which contains two calponin homology domains. We find two...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2002
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199260/ |