RMRP Is a Non-Coding RNA Essential for Early Murine Development
RMRP is a non-coding RNA that is ubiquitously expressed in both humans and mice. RMRP mutations that lead to decreased RMRP levels are found in the pleiotropic syndrome Cartilage Hair Hypoplasia. To assess the effects of deleting RMRP, we engineered a targeting vector that contains loxP sequences f...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198473/ |