RMRP Is a Non-Coding RNA Essential for Early Murine Development

RMRP is a non-coding RNA that is ubiquitously expressed in both humans and mice. RMRP mutations that lead to decreased RMRP levels are found in the pleiotropic syndrome Cartilage Hair Hypoplasia. To assess the effects of deleting RMRP, we engineered a targeting vector that contains loxP sequences f...

Full description

Bibliographic Details
Main Authors: Rosenbluh, Joseph, Nijhawan, Deepak, Chen, Zhao, Wong, Kwok-Kin, Masutomi, Kenkichi, Hahn, William C.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198473/