Divergent effect of mammalian PLCζ in generating Ca2+ oscillations in somatic cells compared with eggs

Divergent effect of mammalian PLCζ in generating Ca2+ oscillations in somatic cells compared with eggs

Sperm PLCζ (phospholipase Cζ) is a distinct phosphoinositide-specific PLC isoform that is proposed to be the physiological trigger of egg activation and embryo development at mammalian fertilization. Recombinant PLCζ has the ability to trigger Ca2+ oscillations when expressed in eggs, but it is not...

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Bibliographic Details
Main Authors: Phillips, Sally V., Yu, Yuansong, Rossbach, Andreas, Nomikos, Michail, Vassilakopoulou, Vyronia, Livaniou, Evangelia, Cumbes, Bevan, Lai, F. Anthony, George, Christopher H., Swann, Karl
Format: Online
Language:English
Published: Portland Press Ltd. 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195308/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195308/

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