Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8+ Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3)
Indoleamine 2,3-dioxygenase (IDO) catalyzes the initial and rate-limiting step of tryptophan catabolism in a specific pathway, resulting in a series of extracellular messengers collectively known as kynurenines. IDO has been recognized as an authentic regulator of immunity not only in mammalian preg...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Libertas Academica
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195250/ |