Investigation on Quantitative Structure Activity Relationships and Pharmacophore Modeling of a Series of mGluR2 Antagonists

Investigation on Quantitative Structure Activity Relationships and Pharmacophore Modeling of a Series of mGluR2 Antagonists

MGluR2 is G protein-coupled receptor that is targeted for diseases like anxiety, depression, Parkinson’s disease and schizophrenia. Herein, we report the three-dimensional quantitative structure–activity relationship (3D-QSAR) studies of a series of 1,3-dihydrobenzo[ b][1,4]diazepin-2-one derivative...

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Bibliographic Details
Main Authors:	Zhang, Meng-Qi, Zhang, Xiao-Le, Li, Yan, Fan, Wen-Jia, Wang, Yong-Hua, Hao, Ming, Zhang, Shu-Wei, Ai, Chun-Zhi
Format:	Online
Language:	English
Published:	Molecular Diversity Preservation International (MDPI) 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189765/

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