A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

Many bacterial pathogens utilize a type III secretion system (T3SS) to inject virulence effector proteins into host cells during infection. Previously, we found that enteropathogenic Escherichia coli (EPEC) uses the type III effector, NleE, to block the inflammatory response by inhibiting IκB degrad...

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Bibliographic Details
Main Authors: Pearson, Jaclyn S, Riedmaier, Patrice, Marchès, Olivier, Frankel, Gad, Hartland, Elizabeth L
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178796/

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