Enteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome Activation

Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) are related strains capable of inducing severe gastrointestinal disease. For optimal infection, these pathogens actively modulate cellular functions through the deployment of effector proteins in a type three secretion system (T...

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Bibliographic Details
Main Authors: Yen, Hilo, Sugimoto, Nakaba, Tobe, Toru
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557958/