The enteropathogenic Escherichia coli effector NleH inhibits apoptosis induced by Clostridium difficile toxin B

Clostridium difficile is a leading cause of nosocomial infections, causing a spectrum of diseases ranging from diarrhoea to pseudomembranous colitis triggered by a range of virulence factors including C. difficile toxins A (TcdA) and B (TcdB). TcdA and TcdB are monoglucosyltransferases that irrevers...

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Bibliographic Details
Main Authors: Robinson, Keith S., Mousnier, Aurelie, Hemrajani, Cordula, Fairweather, Neil, Berger, Cedric N., Frankel, Gad
Format: Online
Language:English
Published: Society for General Microbiology 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068670/