Regulation of TFEB and V-ATPases by mTORC1

Regulation of TFEB and V-ATPases by mTORC1

TORC1 is a key regulator of cell growth in response to nutrients and acts at the surface of the late endosome. This study identifies V-ATPase genes as transcriptional targets of TORC1 and implicates the transcription factor TFEB as an important mediator of TORC1-dependent gene expression and TORC1-r...

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Bibliographic Details
Main Authors: Peña-Llopis, Samuel, Vega-Rubin-de-Celis, Silvia, Schwartz, Jacob C, Wolff, Nicholas C, Tran, Tram Anh T, Zou, Lihua, Xie, Xian-Jin, Corey, David R, Brugarolas, James
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160667/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160667/

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