Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion

mTOR is a central controller for cell growth/proliferation and survival. Recent studies have shown that mTOR also regulates cell adhesion, yet the underlying mechanism is not known. Here we found that inhibition of mTOR by rapamycin reduced the basal or type I insulin-like growth factor (IGF-1)-stim...

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Bibliographic Details
Main Authors: Chen, Long, Xu, Baoshan, Liu, Lei, Liu, Chunxiao, Luo, Yan, Chen, Xin, Barzegar, Mansoureh, Chung, Jun, Huang, Shile
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466674/