The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains

The large diversity in nucleosome-remodelling enzymes evokes great interest in unveiling common mechanistic themes in remodelling reactions. Here, the C-terminus of Chd1 contains a functionally important DNA-binding domain unexpectedly similar to the SANT and SLIDE domains in the ISWI ATPase.

Bibliographic Details
Main Authors: Ryan, Daniel P, Sundaramoorthy, Ramasubramanian, Martin, David, Singh, Vijender, Owen-Hughes, Tom
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155300/