ISWI and CHD Chromatin Remodelers Bind Promoters but Act in Gene Bodies

ATP-dependent nucleosome remodelers influence genetic processes by altering nucleosome occupancy, positioning, and composition. In vitro, Saccharomyces cerevisiae ISWI and CHD remodelers require ∼30–85 bp of extranucleosomal DNA to reposition nucleosomes, but linker DNA in S. cerevisiae averages <...

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Bibliographic Details
Main Authors: Zentner, Gabriel E., Tsukiyama, Toshio, Henikoff, Steven
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585014/