Extension of Lifespan in C. elegans by Naphthoquinones That Act through Stress Hormesis Mechanisms

Hormesis occurs when a low level stress elicits adaptive beneficial responses that protect against subsequent exposure to severe stress. Recent findings suggest that mild oxidative and thermal stress can extend lifespan by hormetic mechanisms. Here we show that the botanical pesticide plumbagin, whi...

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Bibliographic Details
Main Authors: Hunt, Piper R., Son, Tae Gen, Wilson, Mark A., Yu, Quian-Sheng, Wood, William H., Zhang, Yongqing, Becker, Kevin G., Greig, Nigel H., Mattson, Mark P., Camandola, Simonetta, Wolkow, Catherine A.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135594/