Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation

by Tweedie, David, Frankola, Kathryn A., Luo, Weiming, Li, Yazhou, Greig, Nigel H
Published 2011

Rivastigmine Lowers Aβ and Increases sAPPα Levels, Which Parallel Elevated Synaptic Markers and Metabolic Activity in Degenerating Primary Rat Neurons

by Bailey, Jason A., Ray, Balmiki, Greig, Nigel H., Lahiri, Debomoy K.
Published 2011

The Anticholinesterase Phenserine and Its Enantiomer Posiphen as 5′Untranslated-Region-Directed Translation Blockers of the Parkinson's Alpha Synuclein Expression

by Mikkilineni, Sohan, Cantuti-Castelvetri, Ippolita, Cahill, Catherine M., Balliedier, Amelie, Greig, Nigel H., Rogers, Jack T.
Published 2012

TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation

by Belarbi, Karim, Jopson, Timothy, Tweedie, David, Arellano, Carla, Luo, Weiming, Greig, Nigel H, Rosi, Susanna
Published 2012

Acetylcholinesterase inhibition ameliorates deficits in motivational drive

by Martinowich, Keri, Cardinale, Kathleen M, Schloesser, Robert J, Hsu, Michael, Greig, Nigel H, Manji, Husseini K
Published 2012

Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans

by Maccecchini, Maria L, Chang, Mee Young, Pan, Catherine, John, Varghese, Zetterberg, Henrik, Greig, Nigel H
Published 2012

Cognitive Impairments Accompanying Rodent Mild Traumatic Brain Injury Involve p53-Dependent Neuronal Cell Death and Are Ameliorated by the Tetrahydrobenzothiazole PFT-α

by Rachmany, Lital, Tweedie, David, Rubovitch, Vardit, Yu, Qian-Sheng, Li, Yazhou, Wang, Jia-Yi, Pick, Chaim G., Greig, Nigel H.
Published 2013

Exendin-4 Ameliorates Traumatic Brain Injury-Induced Cognitive Impairment in Rats

by Eakin, Katharine, Li, Yazhou, Chiang, Yung-Hsiao, Hoffer, Barry J., Rosenheim, Hilary, Greig, Nigel H., Miller, Jonathan P.
Published 2013

Neuronal Cellular Responses to Extremely Low Frequency Electromagnetic Field Exposure: Implications Regarding Oxidative Stress and Neurodegeneration

by Reale, Marcella, Kamal, Mohammad A., Patruno, Antonia, Costantini, Erica, D'Angelo, Chiara, Pesce, Miko, Greig, Nigel H.
Published 2014

Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice

by Baratz, Renana, Tweedie, David, Wang, Jia-Yi, Rubovitch, Vardit, Luo, Weiming, Hoffer, Barry J, Greig, Nigel H, Pick, Chaim G
Published 2015

Early intervention with a small molecule inhibitor for tumor nefosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer’s disease

by Gabbita, S Prasad, Srivastava, Minu K, Eslami, Pirooz, Johnson, Ming F, Kobritz, Naomi K, Tweedie, David, Greig, Nigel H, Zemlan, Frank P, Sharma, Sherven P, Harris-White, Marni E
Published 2012

Correction: Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels

by Lilja, Anna M., Röjdner, Jennie, Mustafiz, Tamanna, Thomé, Carina M., Storelli, Elisa, Gonzalez, Daniel, Unger-Lithner, Christina, Greig, Nigel H., Nordberg, Agneta, Marutle, Amelia
Published 2013

Neurotrophic and Neuroprotective Actions of (−)- and (+)-Phenserine, Candidate Drugs for Alzheimer’s Disease

by Lilja, Anna M., Luo, Yu, Yu, Qian-sheng, Röjdner, Jennie, Li, Yazhou, Marini, Ann M., Marutle, Amelia, Nordberg, Agneta, Greig, Nigel H.
Published 2013

Evidence of a Novel Mechanism for Partial γ-Secretase Inhibition Induced Paradoxical Increase in Secreted Amyloid β Protein

by Barnwell, Eliza, Padmaraju, Vasudevaraju, Baranello, Robert, Pacheco-Quinto, Javier, Crosson, Craig, Ablonczy, Zsolt, Eckman, Elizabeth, Eckman, Christopher B., Ramakrishnan, Viswanathan, Greig, Nigel H., Pappolla, Miguel A., Sambamurti, Kumar
Published 2014

Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels

by Lilja, Anna M., Röjdner, Jennie, Mustafiz, Tamanna, Thomé, Carina M., Storelli, Elisa, Gonzalez, Daniel, Unger-Lithner, Christina, Greig, Nigel H., Nordberg, Agneta, Marutle, Amelia
Published 2013

In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems

by Beedie, Shaunna L., Rore, Holly M., Barnett, Shelby, Chau, Cindy H., Luo, Weiming, Greig, Nigel H., Figg, William D., Vargesson, Neil
Published 2016

Extension of Lifespan in C. elegans by Naphthoquinones That Act through Stress Hormesis Mechanisms

by Hunt, Piper R., Son, Tae Gen, Wilson, Mark A., Yu, Quian-Sheng, Wood, William H., Zhang, Yongqing, Becker, Kevin G., Greig, Nigel H., Mattson, Mark P., Camandola, Simonetta, Wolkow, Catherine A.
Published 2011

Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis

by Li, Yazhou, Chigurupati, Srinivasulu, Holloway, Harold W., Mughal, Mohamed, Tweedie, David, Bruestle, Daniel A., Mattson, Mark P., Wang, Yun, Harvey, Brandon K., Ray, Balmiki, Lahiri, Debomoy K., Greig, Nigel H.
Published 2012

Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflamma...

by Tweedie, David, Ferguson, Ryan A, Fishman, Kelly, Frankola, Kathryn A, Van Praag, Henriette, Holloway, Harold W, Luo, Weiming, Li, Yazhou, Caracciolo, Luca, Russo, Isabella, Barlati, Sergio, Ray, Balmiki, Lahiri, Debomoy K, Greig, Nigel H, Rosi, Susanna
Published 2012

Critical role of TNF-α in cerebral aneurysm formation and progression to rupture

by Starke, Robert M, Chalouhi, Nohra, Jabbour, Pascal M, Tjoumakaris, Stavropoula I, Gonzalez, L Fernando, Rosenwasser, Robert H, Wada, Kosuke, Shimada, Kenji, Hasan, David M, Greig, Nigel H, Owens, Gary K, Dumont, Aaron S
Published 2014