EndoG Links Bnip3-Induced Mitochondrial Damage and Caspase-Independent DNA Fragmentation in Ischemic Cardiomyocytes
Mitochondrial dysfunction, caspase activation and caspase-dependent DNA fragmentation are involved in cell damage in many tissues. However, differentiated cardiomyocytes repress the expression of the canonical apoptotic pathway and their death during ischemia is caspase-independent. The atypical BH3...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060094/ |