Leishmania infantum EndoG Is an Endo/Exo-Nuclease Essential for Parasite Survival

EndoG, a member of the DNA/RNA non-specific ββα-metal family of nucleases, has been demonstrated to be present in many organisms, including Trypanosomatids. This nuclease participates in the apoptotic program in these parasites by migrating from the mitochondrion to the nucleus, where it takes part...

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Bibliographic Details
Main Authors: Rico, Eva, Oliva, Cristina, Gutierrez, Kilian Jesús, Alzate, Juan Fernando, Genes, Carlos Mario, Moreno, David, Casanova, Elena, Gigante, Alba, Pérez-Pérez, María-Jesús, Camarasa, María-José, Clos, Joachim, Gago, Federico, Jiménez-Ruiz, Antonio
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971528/