Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a predictive factor for response to interferon-alpha therapy and development of hepatocellular carcinoma.

Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a predictive factor for response to interferon-alpha therapy and development of hepatocellular carcinoma.

Genetic changes between codons 2209 and 2248 of NS5A of genotype 1b hepatitis C virus (HCV-1b) have been reported to be associated with the sensitivity to interferon-alpha (IFN-alpha). The present study was performed to analyze such relationship in Korean patients with chronic hepatitis C and HCV-1b...

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Main Authors: Bae, S. H., Park, Y. M., Yoo, D. G., Choi, J. Y., Byun, B. H., Yang, J. M., Lee, C. D., Cha, S. B., Park, D. H., Kim, B. S.
Format: Online
Language:English
Published: Korean Academy of Medical Sciences 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054587/

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