The maintenance of busulphan-induced remissions in chronic granulocytic leukaemia with recombinant interferon alpha-2b.

Interferon (IFN) shows no specificity in inhibiting the growth of colonies of myeloid leukaemia blasts in culture as compared to normal haemopoietic precursors, but does reduce the self-renewal capacity of myeloblasts. We have tested the ability of IFN to slow the leukocyte doubling time (Ldt) and t...

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Bibliographic Details
Main Authors: Bergsagel, D. E., Messner, H.
Format: Online
Language:English
Published: 1990
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971686/