Monitoring antibody titers to recombinant Core-NS3 fusion polypeptide is useful for evaluating hepatitis C virus infection and responses to interferon-alpha therapy.

To evaluate the clinical feasibility of the antibody titer against a chimeric polypeptide (named Core 518), in which a domain of Core and NS3 of hepatitis C virus (HCV) was fused, ELISA was performed in a total of 76 serum samples. Each serum was serially diluted using two-fold dilution method with...

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Bibliographic Details
Main Authors: Park, Y. M., Byun, B. H., Choi, J. Y., Bae, S. H., Kim, B. S., So, H. S., Ryu, W. S.
Format: Online
Language:English
Published: Korean Academy of Medical Sciences 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054362/