A role for Lin28 in primordial germ cell development and germ cell malignancy

A role for Lin28 in primordial germ cell development and germ cell malignancy

The rarity and inaccessibility of the earliest primordial germ cells (PGCs) in the mouse embryo thwarts efforts to investigate molecular mechanisms of germ cell specification. Stella marks the minute founder population of the germ lineage1,2. Here we differentiate mouse embryonic stem cells (ESCs) c...

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Main Authors: West, Jason A., Viswanathan, Srinivas R., Yabuuchi, Akiko, Cunniff, Kerianne, Takeuchi, Ayumu, Park, In-Hyun, Sero, Julia E., Zhu, Hao, Perez-Atayde, Antonio, Frazier, A. Lindsay, Surani, M. Azim, Daley, George Q.
Format: Online
Language:English
Published: 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729657/

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