Rebuilding Pluripotency from Primordial Germ Cells
Mammalian primordial germ cells (PGCs) are unipotent progenitors of the gametes. Nonetheless, they can give rise directly to pluripotent stem cells in vitro or during teratocarcinogenesis. This conversion is inconsistent, however, and has been difficult to study. Here, we delineate requirements for...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757743/ |