SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

Specification of primordial germ cells (PGCs) marks the beginning of the totipotent state. However, without a tractable experimental model, the mechanism of human PGC (hPGC) specification remains unclear. Here, we demonstrate specification of hPGC-like cells (hPGCLCs) from germline competent pluripo...

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Bibliographic Details
Main Authors: Irie, Naoko, Weinberger, Leehee, Tang, Walfred W.C., Kobayashi, Toshihiro, Viukov, Sergey, Manor, Yair S., Dietmann, Sabine, Hanna, Jacob H., Surani, M. Azim
Format: Online
Language:English
Published: Cell Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310934/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310934/

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