A phase I and pharmacokinetic study of amphethinile.
Amphethinile is a new spindle poison with a novel structure that has shown activity in the L1210, ADJ/PC6 and Walker carcinoma rodent tumours. In addition the agent appeared to have an improved therapeutic ratio compared to existing spindle poisons and is well absorbed when administered orally. The...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
1988
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246468/ |