Pre-clinical studies of a novel anti-mitotic agent, amphethinile.
A new antitumour agent is described, which has been shown to induce a G2/M block in murine leukaemia cells in vitro. In addition this agent has been shown to be equally toxic toward parental and daunorubicin-resistant P388 cells in vitro. These resistant cells are highly cross-resistant to the estab...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
1988
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246435/ |