Subfunctionalization of Duplicated Zebrafish pax6 Genes by cis-Regulatory Divergence
Gene duplication is a major driver of evolutionary divergence. In most vertebrates a single PAX6 gene encodes a transcription factor required for eye, brain, olfactory system, and pancreas development. In zebrafish, following a postulated whole-genome duplication event in an ancestral teleost, dupli...
Main Authors: | Kleinjan, Dirk A, Bancewicz, Ruth M, Gautier, Philippe, Dahm, Ralf, Schonthaler, Helia B, Damante, Giuseppe, Seawright, Anne, Hever, Ann M, Yeyati, Patricia L, van Heyningen, Veronica, Coutinho, Pedro |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2008
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242813/ |
Similar Items
-
Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences
by: Ravi, Vydianathan, et al.
Published: (2013) -
Sequencing of Pax6 loci from the elephant shark reveals a family of Pax6 genes in vertebrate genomes, forged by ancient duplications and divergences.
by: Vydianathan Ravi, et al. -
Subfunctionalization of duplicated genes as a transition state to neofunctionalization
by: Rastogi, Shruti, et al.
Published: (2005) -
DNaseI Hypersensitivity and Ultraconservation Reveal Novel, Interdependent Long-Range Enhancers at the Complex Pax6 Cis-Regulatory Region
by: McBride, David J., et al.
Published: (2011) -
DNaseI hypersensitivity and ultraconservation reveal novel, interdependent long-range enhancers at the complex Pax6 cis-regulatory region.
by: David J McBride, et al.