Phylogenetic Analysis of Kindlins Suggests Subfunctionalization of an Ancestral Unduplicated Kindlin into Three Paralogs in Vertebrates
Kindlin proteins represent a newly discovered family of evolutionarily conserved FERM domain-containing proteins. This family includes three highly conserved proteins: Kindlin-1, Kindlin-2 and Kindlin-3. All three Kindlin proteins are associated with focal adhesions and are involved in integrin acti...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Libertas Academica
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072626/ |