IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF
Cytokine receptor signals have been suggested to stimulate cell differentiation during hemato/lymphopoiesis. Such action, however, has not been clearly demonstrated. Here, we show that adult B cell development in IL-7 −/− and IL-7Rα2/− mice is arrested at the pre–pro-B cell stage due to insufficient...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213146/ |