Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors

The mechanism of lineage commitment from hematopoietic stem cells (HSCs) is not well understood. Although commitment to either the lymphoid or the myeloid lineage is popularly viewed as the first step of lineage restriction from HSCs, this model of hematopoietic differentiation has recently been cha...

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Bibliographic Details
Main Authors: Lai, Anne Y., Kondo, Motonari
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118384/