Developmental Stage, Phenotype, and Migration Distinguish Naive- and Effector/Memory-like CD4+ Regulatory T Cells

Regulatory T cells (Tregs) fulfill a central role in immune regulation. We reported previously that the integrin αEβ7 discriminates distinct subsets of murine CD4+ regulatory T cells. Use of this marker has now helped to unravel a fundamental dichotomy among regulatory T cells. αE −CD25+ cells expre...

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Bibliographic Details
Main Authors: Huehn, Jochen, Siegmund, Kerstin, Lehmann, Joachim C.U., Siewert, Christiane, Haubold, Uta, Feuerer, Markus, Debes, Gudrun F., Lauber, Joerg, Frey, Oliver, Przybylski, Grzegorz K., Niesner, Uwe, de la Rosa, Maurus, Schmidt, Christian A., Bräuer, Rolf, Buer, Jan, Scheffold, Alexander, Hamann, Alf
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211798/