Lineage-Restricted Function of Nuclear Factor κB–Inducing Kinase (Nik) in Transducing Signals via Cd40
CD40 signaling in B cells and dendritic cells (DCs) is critical for the development of humoral and cell-mediated immunity, respectively. Nuclear factor κB (NF-κB)–inducing kinase (NIK) has been implicated as a central transducing kinase in CD40-dependent activation. Here, we show that although NIK i...
Main Authors: | Garceau, Norman, Kosaka, Yoko, Masters, Sally, Hambor, John, Shinkura, Reiko, Honjo, Tasuku, Noelle, Randolph J. |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195761/ |
Similar Items
-
Alymphoplasia (aly)-Type Nuclear Factor κB–Inducing Kinase (Nik) Causes Defects in Secondary Lymphoid Tissue Chemokine Receptor Signaling and Homing of Peritoneal Cells to the Gut-Associated Lymphatic Tissue System
by: Fagarasan, Sidonia, et al.
Published: (2000) -
AID to overcome the limitations of genomic information by introducing somatic DNA alterations
by: Honjo, Tasuku, et al.
Published: (2006) -
Assembly and Regulation of the CD40 Receptor Complex in Human B Cells
by: Kuhné, Michelle R., et al.
Published: (1997) -
Collaborative teaching environment system using think-pair-share technique / Nik Azlina bt Nik Mahmood @ Nik Ahmad
by: Nik Mahmood, Nik Azlina
Published: (2008) -
APPL1 regulates basal NF-κB activity by stabilizing NIK
by: Hupalowska, Anna, et al.
Published: (2012)