AID to overcome the limitations of genomic information by introducing somatic DNA alterations

AID to overcome the limitations of genomic information by introducing somatic DNA alterations

The immune system has adopted somatic DNA alterations to overcome the limitations of the genomic information. Activation induced cytidine deaminase (AID) is an essential enzyme to regulate class switch recombination (CSR), somatic hypermutation (SHM) and gene conversion (GC) of the immunoglobulin ge...

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Bibliographic Details
Main Authors: Honjo, Tasuku, Muramatsu, Masamichi, Nagaoka, Hitoshi, Kinoshita, Kazuo, Shinkura, Reiko
Format: Online
Language:English
Published: The Japan Academy 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323042/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323042/

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