Lineage-Restricted Function of Nuclear Factor κB–Inducing Kinase (Nik) in Transducing Signals via Cd40
CD40 signaling in B cells and dendritic cells (DCs) is critical for the development of humoral and cell-mediated immunity, respectively. Nuclear factor κB (NF-κB)–inducing kinase (NIK) has been implicated as a central transducing kinase in CD40-dependent activation. Here, we show that although NIK i...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195761/ |