Identification of a Pre-BCR Lacking Surrogate Light Chain

SLP-65−/− pre-B cells show a high proliferation rate in vitro. We have shown previously that λ5 expression and consequently a conventional pre-B cell receptor (pre-BCR) are essential for this proliferation. Here, we show that pre-B cells express a novel receptor complex that contains a μ heavy chain...

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Bibliographic Details
Main Authors: Su, Yu-wen, Flemming, Alexandra, Wossning, Thomas, Hobeika, Elias, Reth, Michael, Jumaa, Hassan
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194143/