Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

The most common human leukemia is B cell chronic lymphocytic leukemia (CLL), a malignancy of mature B cells with a characteristic clinical presentation but a variable clinical course. The rearranged immunoglobulin (Ig) genes of CLL cells may be either germ-line in sequence or somatically mutated. La...

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Bibliographic Details
Main Authors: Rosenwald, Andreas, Alizadeh, Ash A., Widhopf, George, Simon, Richard, Davis, R. Eric, Yu, Xin, Yang, Liming, Pickeral, Oxana K., Rassenti, Laura Z., Powell, John, Botstein, David, Byrd, John C., Grever, Michael R., Cheson, Bruce D., Chiorazzi, Nicholas, Wilson, Wyndham H., Kipps, Thomas J., Brown, Patrick O., Staudt, Louis M.
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193523/

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