Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell–like diffuse large B cell lymphoma

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell–like diffuse large B cell lymphoma

To elucidate the mechanisms underlying chromosomal translocations in diffuse large B cell lymphoma (DLBCL), we investigated the nature and extent of immunoglobulin class switch recombination (CSR) in these tumors. We used Southern blotting to detect legitimate and illegitimate CSR events in tumor sa...

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Bibliographic Details
Main Authors: Lenz, Georg, Nagel, Inga, Siebert, Reiner, Roschke, Anna V., Sanger, Warren, Wright, George W., Dave, Sandeep S., Tan, Bruce, Zhao, Hong, Rosenwald, Andreas, Muller-Hermelink, Hans Konrad, Gascoyne, Randy D., Campo, Elias, Jaffe, Elaine S., Smeland, Erlend B., Fisher, Richard I., Kuehl, W. Michael, Chan, Wing C., Staudt, Louis M.
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137913/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137913/

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