T Cell Affinity Maturation by Selective Expansion during Infection
T lymphocyte recognition of infected cells is mediated by T cell receptors (TCRs) interacting with their ligands, self–major histocompatibility complex (MHC) molecules complexed with pathogen-derived peptides. Serial TCR interactions with potentially small numbers of MHC/ peptide complexes on infect...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1999
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192934/ |