Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites
In this study, we have identified a dominant glycolipid toxin of Plasmodium falciparum. It is a glycosylphosphatidylinositol (GPI). The parasite GPI moiety, free or associated with protein, induces tumor necrosis factor and interleukin 1 production by macrophages and regulates glucose metabolism in...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1993
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190877/ |