Requirements for glycosylphosphatidylinositol attachment are similar but not identical in mammalian cells and parasitic protozoa

The general features of the glycosylphosphatidylinositol (GPI) signal have been conserved in evolution. To test whether the requirements for GPI attachment are indeed the same in mammalian cells and parasitic protozoa, we expressed the prototype GPI-linked protein of Trypanosoma brucei, the variant...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1994
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120041/