Systemic autoimmune disease arises from polyclonal B cell activation
The number of B cells producing antibodies reactive with any of seven autoantigens or two conventional antigens was compared at the single- cell level to the total number of Ig-secreting B cells present in the spleens of NZB, MRL lpr/lpr, and BXSB autoimmune mice. The proportion of lymphocytes produ...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1987
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188353/ |