Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response

Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response

Anumber of proteins are recruited to nuclear foci upon exposure to double-strand DNA damage, including 53BP1 and Rad51, but the precise role of these DNA damage–induced foci remain unclear. Here we show in a variety of human cell lines that histone deacetylase (HDAC) 4 is recruited to foci with kine...

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Bibliographic Details
Main Authors: Kao, Gary D., McKenna, W. Gillies, Guenther, Matthew G., Muschel, Ruth J., Lazar, Mitchell A., Yen, Tim J.
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172769/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172769/

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