Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours.
Dihydropyrimidine dehydrogenase (DPD) is the rate-limiting enzyme for degradation of 5-fluorouracil (5-FU). DPD activity is highly variable in liver and peripheral mononuclear cells (PMNCs) and it has not been well studied in human tumours. Characterization of DPD in colorectal cancer is of clinical...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
1998
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151304/ |