Screening of Dihydropyrimidine Dehydrogenase Genetic Variants by Direct Sequencing in Different Ethnic Groups

Screening of Dihydropyrimidine Dehydrogenase Genetic Variants by Direct Sequencing in Different Ethnic Groups

Dihydropyrimidine dehydrogenase (DPYD) is an enzyme that regulates the rate-limiting step in pyrimidine metabolism, especially catabolism of fluorouracil, a chemotherapeutic agent for cancer. In order to determine the genetic distribution of DPYD, we directly sequenced 288 subjects from five ethnic...

Full description

Bibliographic Details
Main Authors: Shin, Joong-Gon, Cheong, Hyun Sub, Kim, Jason Yongha, Kim, Lyoung Hyo, Han, Chang Soo, Kim, Ji On, Kim, Hae Deun, Kim, Young Hoon, Chung, Myeon Woo, Han, Soon Young, Shin, Hyoung Doo
Format: Online
Language:English
Published: The Korean Academy of Medical Sciences 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744698/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744698/

Similar Items