Agrin Can Mediate Acetylcholine Receptor Gene Expression in Muscle by Aggregation of Muscle-derived Neuregulins

The neural isoforms of agrin can stimulate transcription of the acetylcholine receptor (AChR) ε subunit gene in electrically active muscle fibers, as does the motor neuron upon the formation of a neuromuscular junction. It is not clear, however, whether this induction involves neuregulins (NRGs), wh...

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Bibliographic Details
Main Authors: Meier, Thomas, Masciulli, Fabrizio, Moore, Chris, Schoumacher, Fabrice, Eppenberger, Urs, Denzer, Alain J., Jones, Graham, Brenner, Hans Rudolf
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132745/