ICAP-1, a Novel β1 Integrin Cytoplasmic Domain–associated Protein, Binds to a Conserved and Functionally Important NPXY Sequence Motif of β1 Integrin

The cytoplasmic domains of integrins are essential for cell adhesion. We report identification of a novel protein, ICAP-1 (integrin cytoplasmic domain– associated protein-1), which binds to the β 1 integrin cytoplasmic domain. The interaction between ICAP-1 and β1 integrins is highly specific, as de...

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Bibliographic Details
Main Authors: Chang, David D., Wong, Carol, Smith, Healy, Liu, Jenny
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136751/