Frequent and specific immunity to the embryonal stem cell–associated antigen SOX2 in patients with monoclonal gammopathy

Frequent and specific immunity to the embryonal stem cell–associated antigen SOX2 in patients with monoclonal gammopathy

Specific targets of cellular immunity in human premalignancy are largely unknown. Monoclonal gammopathy of undetermined significance (MGUS) represents a precursor lesion to myeloma (MM). We show that antigenic targets of spontaneous immunity in MGUS differ from MM. MGUS patients frequently mount a h...

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Main Authors: Spisek, Radek, Kukreja, Anjli, Chen, Lin-Chi, Matthews, Phillip, Mazumder, Amitabha, Vesole, David, Jagannath, Sundar, Zebroski, Henry A., Simpson, Andrew J.G., Ritter, Gerd, Durie, Brian, Crowley, John, Shaughnessy, John D., Scanlan, Matthew J., Gure, Ali O., Barlogie, Bart, Dhodapkar, Madhav V.
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118551/

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