Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-γ–mediated pathways

Interleukin (IL)-27 is the newest member of the IL-12 family of heterodimeric cytokines composed of the Epstein-Barr virus–induced gene 3 and p28 chains. IL-27 not only plays an important role in the regulation of differentiation of naive T helper cells but also possesses antiinflammatory properties...

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Bibliographic Details
Main Authors: Liu, Jianguo, Guan, Xiuqin, Ma, Xiaojing
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118415/