IL-1R–MyD88 signaling in keratinocyte transformation and carcinogenesis

Keratinocyte MyD88 is a component of an IL-1α–IL-1R autocrine loop that drives Ras-mediated transformation in vitro and contributes to skin tumor formation in vivo.

Bibliographic Details
Main Authors: Cataisson, Christophe, Salcedo, Rosalba, Hakim, Shakeeb, Moffitt, B. Andrea, Wright, Lisa, Yi, Ming, Stephens, Robert, Dai, Ren-Ming, Lyakh, Lyudmila, Schenten, Dominik, Yuspa, H. Stuart, Trinchieri, Giorgio
Format: Online
Language:English
Published: The Rockefeller University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428947/