Alternative activation of macrophages by filarial nematodes is MyD88-independent

Alternative macrophage activation is largely defined by IL-4Rα stimulation but the contribution of Toll-like receptor (TLR) signaling to this phenotype is not currently known. We have investigated macrophage activation status under Th2 conditions in the absence of the core TLR adaptor molecule, MyD8...

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Bibliographic Details
Main Authors: Mylonas, Katie J., Hoeve, Marieke A., MacDonald, Andrew S., Allen, Judith E.
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608026/