Structural and Functional Characterization of the Human Protein Kinase ASK1

Structural and Functional Characterization of the Human Protein Kinase ASK1

Apoptosis signal-regulating kinase 1 (ASK1) plays an essential role in stress and immune response and has been linked to the development of several diseases. Here, we present the structure of the human ASK1 catalytic domain in complex with staurosporine. Analytical ultracentrifugation (AUC) and crys...

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Bibliographic Details
Main Authors: Bunkoczi, Gabor, Salah, Eidarus, Filippakopoulos, Panagis, Fedorov, Oleg, Müller, Susanne, Sobott, Frank, Parker, Sirlester A., Zhang, Haifeng, Min, Wang, Turk, Benjamin E., Knapp, Stefan
Format: Online
Language:English
Published: Cell Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100151/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100151/

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